This herbaceous plant is not only used to produce beer! With all due respect to zythologists (« beer oenologists », experts in brewing and taste tuning), it is also used in phytotherapy. Its female flowers (especially the cones) are covered with an odorous, powdery substance called lupulin, which gives beer its bitterness, but above all it is said to have calming properties that promote sleep.
Rich in flavonoids (rutoside, astragaloside, chalcones and quercitroside), the plant also contains an essence composed of monoterpenes, monoterpenols and sesquiterpenes.
Hops is particularly indicated in the fight against menopausal disorders, especially in the case of hot flushes. It has oestrogen-like properties, thanks in particular to the presence of 8-prenylnaringenin (8-PN), known for its powerful oestrogenic action. 8-PN is in fact the most powerful phytoestrogen known to date. Hops also provide 6-prenylnaringene, xanthohumol and isoxanthohumol. The latter is a weak phytoestrogenic molecule but is bio-activated by 8-PN with the help of microbiota. Hops also have sedative and analgesic properties.
Traditionally used in menopausal women, hops help to support associated signs such as hot flushes, anxiety, agitation, but also irritability and mood disorders. The presence of humulone allows the modulation of GABA inhibitory receptors and a calming of the nervous system, thus promoting sleep.
THERASCIENCE specific features
For PHYSIOMANCE Oestronat, the THERASCIENCE Laboratory has selected the patented hop extract Lifenol®, standardised in 8-prenylnaringenin and with clinically proven efficacy on the symptoms associated with the menopause, particularly hot flushes.
Hops are the subject of more than 688 scientific publications.
The selection of our active ingredients is constantly guided by numerous scientific publications, based on randomised double-blind clinical studies versus placebo, in humans, guaranteeing a real scientific value. The doctors, pharmacists and engineers of the THERASCIENCE Laboratory have selected some of these publications for you :
- Aghamiri, Vida et al. “The effect of Hop (Humulus lupulus L.) on early menopausal symptoms and hot flashes: A randomized placebo-controlled trial.” Complementary therapies in clinical practice vol. 23 (2016): 130-5 ;
- Erkkola, R et al. “A randomized, double-blind, placebo-controlled, cross-over pilot study on the use of a standardized hop extract to alleviate menopausal discomforts.” Phytomedicine : international journal of phytotherapy and phytopharmacology vol. 17,6 (2010): 389-96 ;
- Heyerick, Arne et al. “A first prospective, randomized, double-blind, placebo-controlled study on the use of a standardized hop extract to alleviate menopausal discomforts.” Maturitas vol. 54,2 (2006): 164-75.