PQQ
PQQ: the new bio-active anti-ageing agent
- Highly concentrated PQQ* formula: 20 mg ;
- PQQ* from natural fermentation, 99% purified ;
- Clean Label THERASCIENCE;
- Capsules 100% of plant origin.
*PQQ: Disodium salt of pyrroloquinoline quinone
PQQ: the new bio-active anti-ageing agent
*PQQ: Disodium salt of pyrroloquinoline quinone
The mitochondrial function evolves throughout life and can be progressively impacted by physiological ageing as well as by various environmental and behavioural factors. Mitochondria ensure the production of ATP, which is essential for tissue function. Over time, the accumulation of oxidative damage, the decrease in renewal mechanisms (mitophagy) and the reduction in mitochondrial biogenesis lead to a higher proportion of less efficient mitochondria. This phenomenon contributes to a decrease in cellular energy, promoting fatigue, metabolic slowdown and certain processes associated with cellular ageing. Preserving mitochondrial quality and renewal therefore appears to be a central issue.
PHYSIOMANCE® PQQ is a highly dosed single ingredient containing PyrroloQuinoline Quinone (20 mg per capsule).
Formulated with pure PQQ from fermentation, purified to 99%, and with organic acacia gum as its only excipient, PHYSIOMANCE® PQQ is part of a targeted dietary supplement approach, allowing personalised support and precise dosing.
The PHYSIOMANCE® PQQ formula in 100% plant-based capsules is suitable for vegan diets, and the formula is lactose-free and gluten-free, thus meeting the expectations of consumers attentive to the quality and tolerability of dietary supplements.
Scientific publications, including the review by Akagawa et al. (2016), highlight its potential involvement in mitochondrial biogenesis and in ATP production; as such, PQQ is of particular interest in nutritional strategies dedicated to cellular vitality, sustainable energy and support of cognitive functions. However, to date, no specific health claim is authorised in Europe for PQQ. Its use as a dietary supplement for mitochondria is based on scientific data from experimental and exploratory clinical studies.


The clinical studies available on PQQ (pyrroloquinoline quinone) as a dietary supplement have mainly evaluated a dose of 20 mg per day, administered for 8 to 12 weeks. A randomised, double-blind, placebo-controlled study notably used 20 mg/day for 12 weeks and observed effects on certain parameters of cognitive function (Nakano et al., 2012). Other clinical studies have evaluated 20 mg/day for 8 weeks, with observations on fatigue, stress and sleep quality (Harris et al., 2013).
Mechanistic research also suggests a potential role of PQQ in mitochondrial biogenesis and in supporting cellular energy metabolism (Akagawa et al., 2016), which explains its interest in nutritional strategies focused on mitochondrial vitality.
In a high-quality dietary supplement, the origin and manufacturing process of the molecule are determining factors. PQQ from fermentation has the advantage of being obtained through a controlled biotechnological process, allowing the production of a molecule identical to that naturally present in food, while ensuring high consistency of quality. Fermentation provides better control of production parameters, limits contaminants and makes it possible to obtain a highly purified PQQ, with a high degree of purity and complete traceability.
This process helps ensure the stability, safety and reproducibility of the dosage, essential criteria for a dietary supplement of choice. A natural, purified and standardised PQQ is therefore part of a rigorous approach, combining biotechnological innovation and pharmaceutical-quality requirements.


PHYSIOMANCE® PQQ is part of a demanding approach to a natural and purified dietary supplement, with particular attention paid to the origin of ingredients and the quality of excipients. The formula contains a 100% natural excipient: organic acacia gum, recognised for its tolerability and plant-based origin, and is packaged in 100% plant-based capsules, suitable for specific diets: vegan and vegetarian. This approach combines enhanced naturality, composition transparency and qualitative requirements.
Discover the single ingredients by Therascience, developed by our Laboratory expert in Physionutrition.
To ensure targeted, effective supplementation adapted to each need, Laboratoire THERASCIENCE offers a wide range of single-ingredient formulas, including PHYSIOMANCE® PQQ, guaranteeing the pharmaceutical quality of raw materials and dosing precision.
The single ingredients by Therascience allow:
With PHYSIOMANCE® PQQ, the choice of a single ingredient is part of a personalised micronutrition approach, combining precision, safety and efficacy.

1 capsule per day, for a minimum of 1 month. Repeat if necessary.
Precautions for use :
For adults only. Not recommended for pregnant or breast-feeding women. Store in a cool, dry and dark place.
Food supplements should be used as part of a healthy lifestyle and not as a substitute for a varied and balanced diet. Do not exceed the recommended daily doses. Keep the product out of the reach of young children. In case of combination of several dietary supplements, ask your health professional for advice. Store in a cool, dry and dark place.
Bulking agent : acacia gum*, plant origin coating, pyrroloquinoline quinone disodium salt.
*produced from organic farming
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For 1 capsule |
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PQQ (pyrroloquinoline quinone disodium salt) |
20,0 mg |