SEPISMART^™ SR : A TECHNOLOGY ALLOWING A RAPID AND EXTENDED RELEASE OF THE ACTIVE INGREDIENTS

THERASCIENCE Laboratory uses the patented Sepismart™ SR technology for its PHYSIOMANCE Sommeil LP product in the form of a bi-layer tablet.

 

This bi-layer tablet consists of :

• A white layer containing melatonin and magnesium in citrate form,
• A blue layer containing melatonin, magnesium (in citrate form), eschscholzia (California poppy), vitamins B6 and B12 (in coenzyme form), and benefiting from Sepismart™ SR technology.

THE PROCESS

Sepismart™SR technology is a synergistic combination of naturally occurring xanthan and acacia gums.

 

• Xanthan gum (polysaccharide) is selected for its viscosity properties allowing an extended
• Acacia gum (polysaccharide) is ideal for direct compression, it is a manufactured technique that gives the tablet optimal hardness, thus contributing to a prolonged and gradual release of the active ingredients.

Sepismart™ SR is obtained through an environmentally friendly process (solvent-free) and is guaranteed to be of natural origin, GMO-free and additive-free.

 

On contact with saliva and digestive juices, the tablet disintegrates. Sepismart™ SR technology then comes into action by forming a hydrophilic matrix around the blue layer of the tablet, which allows for an extended release of the active ingredients.

The active ingredients will then be released in 2 phases:

1. The white layer of the tablet disintegrates first, favoring the rapid release of a part of the melatonin and magnesium.
2. Thanks to the SEPISMART™ SR technology, the blue layer allows an extended release of the other part of the melatonin and magnesium, as well as eschscholzia and vitamins B6 and B12.

 

THE BENEFITS

Sepismart™ SR technology allows the prolonged release of melatonin and magnesium at a constant rate. This prolongs the duration of their effects, thus avoiding night-time awakenings.

The extended release of melatonin mimics the natural secretion process of this hormone and thus helps to optimise sleep cycles for a better quality sleep.