Vitamine B9

Highly Concentrated Formula

During pregnancy and breastfeeding, the need for vitamin B9 increases significantly. Indeed, this vitamin plays a crucial role in the development of the fetal nervous system, especially during the early weeks of pregnancy. Sufficient intake of vitamin B9 helps reduce the risk of neural tube defects. That is why health authorities recommend a daily supplementation of 600 µg for pregnant women and 500 µg for breastfeeding women. An adequate supplementation, started at least one month before conception and continued up to 3 months after conception, is often recommended to ensure optimal intake.
Beyond the risk of embryonic malformation in women of childbearing age, a deficiency in vitamin B9 can manifest as severe fatigue, anemia, or more serious symptoms.

PHYSIOMANCE^® Vitamine B9 provides 600 µg of calcium L-methylfolate per capsule, which is 300% of the reference intake for vitamin B9.

Optimal Bioavailability

THERASCIENCE Laboratory prioritizes active ingredients in their most bioavailable forms to ensure optimal absorption and assimilation in the body.

Bioavailability refers to the amount of a substance that reaches the bloodstream or the site of action in the body after being administered or consumed. The higher the bioavailability, the more efficiently the vitamin is absorbed. That is why we systematically choose coenzymated vitamins, minerals in the form of organic salts, and bioactive compounds directly assimilable by the cells.
The vitamin B9 used in PHYSIOMANCE^® Vitamine B9 is in its coenzymated form: calcium L-methylfolate, also known as 5-MTHF (5-methyltetrahydrofolate). This form has better bioavailability than dietary folates and folic acid, ensuring immediate activation and requiring no further transformation once in the body. It can therefore be used immediately in metabolic reactions, leading to enhanced effectiveness. 

For absorption by the body, dietary folates and synthetic folic acid must first be converted into simpler forms by an enzyme in the intestine. Once this step is completed, they are transported into the cells within the enterocytes, where they can be converted into 5-MTHF, the biologically active form of vitamin B9. 

However, some individuals have a genetic variation that limits their ability to perform this conversion, reducing the effectiveness of traditional folic acid metabolism and making the assimilation of vitamin B9 less than optimal. In these cases, direct supplementation with 5-MTHF provides a more suitable solution to ensure efficient and usable intake by the body. The L-methylfolate form of calcium also helps quickly address deficiencies, offering a more effective approach to supply the body with essential elements for many metabolic reactions, while ensuring numerous significant benefits in terms of absorption, efficacy, and stability.

Single-Ingredient Supplement

Discover Therascience’s single-ingredient range, developed by our laboratory, experts in Physionutrition! To ensure effective supplementation tailored to each individual’s needs, the THERASCIENCE Laboratory offers a wide range of single-ingredient formulas, always guaranteeing product quality and the efficacy of its active ingredients.

Therascience’s single-ingredient supplements offer:

• Personalized supplementation tailored to your specific needs,
• Precise and targeted solutions,
• Supplementation without the risk of potential overdoses of certain vitamins, minerals, or trace elements.

Enhanced naturalness

Safe use in case of intolerances
THERASCIENCE Laboratory adapts to all dietary habits: PHYSIOMANCE^® Vitamin B9 is guaranteed gluten-free and lactose-free.

PHYSIOMANCE^® Vitamin B9 is designed with a 100% plant-based capsule shell. HPMC (hydroxypropylmethylcellulose or hypromellose) is the main material used to form the shell of the plant-based capsules. HPMC is a derivative of cellulose, a natural substance found in plant cell walls. It is widely used in the formulation of dietary supplements due to its remarkable properties and safety for health, offering an effective alternative to traditional gelling agents of animal or synthetic origin. One of the main advantages of HPMC is its biodegradability, making it an environmentally friendly choice compared to other coating materials. By using HPMC as an excipient, the THERASCIENCE Laboratory can guarantee not only the safe and effective delivery of the product but also meet growing consumer concerns about quality, safety, and sustainability.