CCGA

Vitamin B9 in the form of calcium L-methylfolate

Vitamin B9, or folate, plays a central role in the folate cycle, an essential biological process involved in numerous body functions. It contributes in particular to the normal growth of maternal tissues during pregnancy, DNA synthesis, cell division, and the normal functioning of the immune and nervous systems. It is also involved in the normal metabolism of homocysteine, a marker of cardiovascular health.
As a water-soluble vitamin, B9 is not stored in the body and must therefore be provided regularly. A folate deficiency in pregnant women increases the risk of neural tube defects in the fetus. Since modern diets are often low in micronutrients, it may be difficult to reach recommended intake levels without supplementation.

The vitamin B9 used in PHYSIOMANCE^® CCGA is in a coenzymated form: calcium L-methylfolate, also known as 5-MTHF (5-methyltetrahydrofolate). This is the biologically active form of vitamin B9, directly usable by the body without prior conversion. This form provides superior bioavailability compared to dietary folates or synthetic folic acid, ensuring rapid absorption and enhanced metabolic efficiency.

In contrast, standard folic acid requires several transformation steps in the intestine before being converted into 5-MTHF. This process depends on a specific enzyme and may be partially ineffective in some individuals. In fact, about 40 to 60% of the population has a genetic variation in the MTHFR gene that limits the conversion of folic acid to its active form. Result: vitamin B9 absorption can be impaired, even when intake is adequate.

Sustainable, pure fish oil rich in omega-3

Omega-3 fatty acids, particularly DHA (docosahexaenoic acid), play a key role during pregnancy and breastfeeding. A daily intake of DHA in pregnant or breastfeeding women contributes to the normal development of the brain and eyes of the fetus and breastfed infant. That’s why targeted nutritional intake is essential from pregnancy through the end of breastfeeding.

The fish oil used in PHYSIOMANCE^® CCGA comes from small wild fish (herring, sardines, anchovies), naturally rich in EPA and DHA omega-3s. As they are low on the food chain, they provide high levels of essential fatty acids and a very low risk of heavy metal contamination, ensuring optimal purity. This oil is extracted under strict standards and certified by Epax^®, a global benchmark for pharmaceutical-grade quality, with a TotOx index < 4 ensuring maximum stability. It also holds the XO^® label, a mark of excellence in quality, traceability, and omega-3 concentration. The fish are sourced from oceanic zones known for their purity, including the Pacific Ocean and the North Sea, and are responsibly fished in accordance with the strict standards of the Friend of the Sea^® label, ensuring marine ecosystem protection and the preservation of fishery resources.

A fully traceable supply chain, from fishing to the finished product, ensures unmatched transparency. This high level of quality meets the expectations of pregnant, breastfeeding, or conceiving women who are mindful of their health and that of their future child.

Micronutritional Complex: Essential Micronutrients for Fertility, Pregnancy, and Breastfeeding

Micronutrients are essential to support the specific needs of women starting from the desire to conceive. Targeted supplementation helps prevent deficiencies and protect the health of both mother and child.
PHYSIOMANCE^® CCGA provides the Suvimine 13^® micronutritional complex, developed by Laboratoire THERASCIENCE, composed of 11 vitamins including B vitamins (B1, B2, B3, B5, B6, B8, B9, B12), C, D, and E, along with 2 trace elements (selenium and zinc), completed by iodine and chromium.
B vitamins include 8 essential nutrients: B1, B2, B3, B5, B6, B8, B9, and B12. These water-soluble vitamins are quickly eliminated by the body, making daily intake essential, especially during maternity.
Zinc is an essential trace element, a cofactor for over 300 enzymes involved in numerous biological functions. It contributes to normal fertility and reproduction, and also plays a role in protein synthesis and cell division.

• Normal immune system function: During pregnancy, natural defenses can be weakened, which is why providing vitamins C (ascorbic acid), D3, and zinc—contributing to normal immune function—is crucial.
• Energy metabolism, fatigue reduction, and nervous system: B vitamins play a vital role in supporting energy metabolism, reducing fatigue, and maintaining normal nervous system function. Vitamin C also helps reduce fatigue, which is common in pregnant women.

• Maintenance of normal bone structure: Vitamin D and zinc contribute to maintaining normal bones, which is crucial during pregnancy and breastfeeding. In areas with low sunlight or in urban environments, vitamin D levels are particularly low, affecting 30 to 60% of the population. Supplementation is therefore essential to maintain optimal levels.
• Protecting cells from oxidative stress: Pregnancy is a time of intense metabolic activity, which can increase oxidative stress. Selenium is an essential trace element that helps protect cells against oxidative stress by neutralizing free radicals. Vitamin E, or tocopherol, is a fat-soluble vitamin known for its antioxidant properties. It can also be regenerated by vitamin C. By neutralizing free radicals, selenium and vitamin E help preserve cell membranes.
• Normal thyroid hormone production: Iodine is an essential trace element required for the normal production of thyroid hormones. These hormones are essential for growth, metabolism, and nervous system development. Selenium also supports normal thyroid function.
• Maintenance of normal blood glucose levels: Gestational diabetes is a temporary form of diabetes that occurs during pregnancy, typically in the second or third trimester, and resolves after childbirth. It affects around 10% of pregnancies in Europe, with prevalence steadily increasing. This glycemic disorder can impact the health of both mother and child. Chromium, an essential trace element, helps maintain normal blood sugar levels. It also plays a role in the normal metabolism of macronutrients, contributing to sugar regulation and supporting insulin action.

Micronutrient supplementation is therefore often necessary to meet the increased needs of pregnant or breastfeeding women.

Excellent Bioavailability for Maximum Efficacy Starting from Preconception

Laboratoire THERASCIENCE favors ingredients in their most bioavailable forms for better absorption and assimilation in the body. We consistently choose coenzymated vitamins, minerals in organic salt forms, standardized plant extracts and powders with active compounds, and bioactive substances directly assimilable by cells:

• Zinc is in the form of bisglycinate, a highly bioavailable form that is very well tolerated by the body.
• Selenium is in the form of selenomethionine, naturally produced by yeast (Saccharomyces cerevisiae) that converts selenite into organic selenium, bound to an essential amino acid, methionine.
• Vitamins B2, B6, B9, and B12, which are water-soluble, are present in coenzymated forms, directly usable by the body: Vitamin B2 as riboflavin-5’-phosphate sodium; Vitamin B6 as pyridoxal-5’-phosphate; Vitamin B9 as L-methylfolate calcium; Vitamin B12 as methylcobalamin.
• Chromium is provided in picolinate form, ensuring optimal bioavailability and effective assimilation by the body.
• The omega-3s in PHYSIOMANCE^® CCGA are in their natural triglyceride form—a stable, oxidation-resistant structure that is directly assimilable by the body. This natural form maximizes the physiological benefits of omega-3s.

Quality Guaranteed by Labels: A Commitment to Excellence

Treat yourself to the best with PHYSIOMANCE^® CCGA, a natural formula aligned with the THERASCIENCE^® Clean Label!

Our products are developed with a genuine focus on the quality and effectiveness of active ingredients. For enhanced naturalness, PHYSIOMANCE^® CCGA provides natural vitamins D3 and E.

Moreover, Laboratoire THERASCIENCE adapts to all dietary habits: PHYSIOMANCE^® CCGA is guaranteed free from gluten- and lactose-based ingredients.