Weight loss is a complex process that goes beyond the reduction of fat mass. Adipose tissue is not only an energy reserve: it also serves as a storage site for many lipophilic substances, including persistent organic pollutants (POPs) and heavy metals.
POPs include compounds such as polybrominated flame retardants (BFRs), organochlorine pesticides (DDT, aldrin, chlordane, etc.), PCBs (polychlorobiphenyls) and dioxins. Their lipophilic nature promotes their accumulation in adipocytes, where they can remain for many years. Similarly, heavy metals, bound to organic ligands, can accumulate in the liver, kidneys, brain, and even fatty tissues.
During a weight-loss phase, the mobilization of fats leads to the release of these substances into the bloodstream.
Faced with this exposure, and to preserve internal balance, the body activates a set of elimination mechanisms known as detoxification. This process, mainly orchestrated by the liver, transforms molecules that are often liposoluble (difficult to eliminate) into water-soluble forms that are more easily excreted through the urine via the kidneys or through the intestines via bile and then the stool.
Detoxification occurs in three successive and complementary stages. First, during Phase I, known as the activation phase, specialized enzymes—particularly those of the cytochrome P450 family—modify the chemical structure of toxins to prepare them for Phase II. Next, Phase II, called conjugation, consists of associating these molecules with natural compounds such as glutathione or certain amino acids (like L-cysteine or methionine) to make them water-soluble. Finally, Phase III corresponds to elimination. The transformed substances are taken up by transport systems and directed towards excretory pathways such as the intestines, urine, or sweat, to be permanently expelled from the body.
DETOXSSENTIEL® Minceur has been specifically formulated to support these physiological mechanisms during weight loss. Its synergy of active compounds provides micronutrients and plant extracts such as orthosiphon, which contributes to proper liver function and supports weight loss alongside dietary measures; pilosella, which supports the body’s elimination functions and stimulates the removal of water and toxins; as well as artichoke, which stimulates the body’s elimination function and promotes weight loss.
Why choose DETOXSSENTIEL® Minceur?
DETOXSSENTIEL® Minceur is based on a synergy of 5 rigorously selected bio-actives and 3 amino acids and derivatives. Per sachet, the formula provides 450 mg of betaine HCI, 500 mg of broccoli extract standardized in sulforaphanes, 500 mg of orthosiphon extract, 300 mg of pilosella extract, 450 mg of artichoke extract standardized in cynarin, 2 g of glycine, 200 mg of reduced L-glutathione, and 100 mg of taurine.
As part of a commitment to quality, DETOXSSENTIEL® Minceur is formulated without nanoparticles, without colorants, and without lactose- or gluten-based ingredients, and is suitable for people following a vegan diet. The flavors and sweeteners are of natural origin.
DETOXSSENTIEL® Minceur is guaranteed Clean Label and High Quality Process®, which highlight the rigorous selection of plants, optimal microbiological quality, and the use of standardized extracts for scientifically controlled effectiveness.
Packaged in convenient lemon–lime flavored sachets, DETOXSSENTIEL® Minceur offers an effective and natural solution.
What does science say?
The bio-actives found in DETOXSSENTIEL® Minceur have undergone an in-depth scientific evaluation by the European Food Safety Authority (EFSA):
- - Betaine HCl contributes to normal homocysteine metabolism;
- - Orthosiphon supports proper liver function and helps facilitate weight loss when combined with dietary measures;
- - Artichoke stimulates the body’s elimination function and promotes weight loss;
- - Pilosella supports the body's elimination functions and acts as a depurative by stimulating the removal of water and toxins.
Broccoli extract, reduced glutathione, taurine and glycine have been the subject of extensive scientific research, and their biological mechanisms of action are well documented in the literature. However, to date, European legislation has not validated any health claims. Although no specific benefit is officially recognized, these active compounds are generating increasing interest and open up promising avenues that deserve further exploration.
The advantages of DETOXSSENTIEL® Minceur
Betaine HCl: Role, benefits and action on homocysteine metabolism
Betaine is a compound naturally present in certain foods, including beetroot, spinach and whole grains.
This bio-active plays a key role as a methyl group donor. These small chemical structures (–CH₃) are transferred from one molecule to another to modify, activate or deactivate specific biological functions. In this context, betaine donates a methyl group to homocysteine to convert it into methionine, thus contributing to the normal metabolism of homocysteine.
Homocysteine is a sulfur-containing amino acid produced by the body during the breakdown of methionine. Maintaining it at a balanced level is essential, as an excess may be associated with increased oxidative stress. By promoting its recycling, betaine therefore contributes to the maintenance of this metabolic balance.
Broccoli extract (Brassica oleracea), standardized in sulforaphanes
Broccoli is a vegetable from the cruciferous family, traditionally consumed for its nutritional properties. It contains a specific sulfur-containing compound: glucoraphanin, which is then converted into sulforaphane, a widely studied compound. The broccoli extract used in DETOXSSENTIEL® Minceur is standardized to 50 mg of sulforaphane (per sachet), a molecule naturally present in young broccoli, particularly sprouted seeds. This ensures that the sulforaphane content is guaranteed, high and consistent, ensuring the broccoli’s effectiveness.
Orthosiphon extract
Orthosiphon (Orthosiphon stamineus) is an herbaceous plant from the Lamiaceae family, native to Southeast Asia, where it is widely cultivated and used in traditional medicine. Easily recognizable by its white or purple flowers with long whisker-like stamens, it is often referred to as “Java tea.” In traditional phytotherapy, orthosiphon is used to support proper liver function and facilitate weight loss alongside dietary measures. Its leaves contain various active compounds, notably flavonoids and polyphenols, which explain its relevance for liver and digestive health.
Artichoke extract standardized in cynarin
Artichoke (Cynara scolymus) is a perennial plant from the Asteraceae family, cultivated since Antiquity around the Mediterranean basin. Appreciated both as a vegetable and for its medicinal properties, it is rich in phenolic compounds, including cynarin, which is responsible for part of its beneficial effects. Traditionally, artichoke is used to stimulate the body’s elimination function, promote weight loss, and help reduce blood lipid levels.
The artichoke extract used in DETOXSSENTIEL® Minceur is standardized to 22.5 mg of cynarin per sachet, ensuring a high and consistent content of this key compound essential to the artichoke’s effectiveness.
Pilosella extract
Pilosella (Hieracium pilosella) is a perennial plant from the Asteraceae family, traditionally used in Europe for its draining and depurative properties. It is known for its richness in flavonoids and bitter principles. In traditional phytotherapy, pilosella is used to promote the body’s elimination functions, particularly at the renal level. It helps to stimulate the natural elimination of water and toxins without disturbing mineral balance. The extract used is obtained from the aerial parts of the plant.
3 Amino acids and derivatives: Reduced L-glutathione, glycine, taurine
DETOXSSENTIEL® Minceur incorporates a targeted combination of 3 amino acids and derivatives, some of which are involved in the metabolism of sulfur-containing compounds:
- Reduced L-glutathione is a small tripeptide molecule naturally synthesized in the liver, composed of glycine, cysteine, and glutamic acid. Its role is widely recognized in biochemistry as a cofactor in cellular enzymatic processes.
- Glycine, naturally abundant in connective tissues, is a component of many proteins, including collagen. It also participates in the formation of peptides and coenzymes.
- Taurine is naturally synthesized by the body from L-cysteine. It is abundantly present in muscle tissues, the brain, and other organs. Although it is not strictly classified as an amino acid, it is involved in various physiological metabolic processes.
All of these compounds are integrated into the formulation of DETOXSSENTIEL® Minceur to support the body’s physiological functions.
Standardized extracts for optimal effectiveness
The THERASCIENCE Laboratory has selected highly concentrated plant extracts. Each sachet provides a synergy of premium ingredients, obtained through controlled extraction processes allowing for high ratios. Thus, one sachet of DETOXSSENTIEL® Slimness contains:
- 500 mg of broccoli extract, with an extraction ratio of 30:1, equivalent to 15 g of dried plant;
- 450 mg of artichoke extract, with a ratio of 4:1, equivalent to 1.8 g of dried plant;
- 500 mg of orthosiphon extract, with a ratio of 4:1, equivalent to 2 g of dried plant;
- 300 mg of mouse-ear hawkweed extract, with a ratio of 4:1, equivalent to 1,200 mg of dried plant.
Thanks to this standardization and a rigorous manufacturing process, each extract offers consistent quality, ensuring precise dosing of active molecules. This standardization enables optimal effectiveness, an essential condition for a high-quality dietary supplement.
An eco-friendly and natural formulation
DETOXSSENTIEL® Slimness reflects the THERASCIENCE Laboratory’s commitment to enhanced naturalness and responsible formulation.
This dietary supplement is formulated without added sugar, without colorants, and exclusively with natural flavors. It contains no controversial excipients, no gluten- or lactose-based ingredients, and is perfectly suitable for vegetarian and vegan diets. Every formulation choice meets a dual requirement: ensuring the product’s safety and effectiveness while respecting the body and the environment. This quest for purity reflects the desire to offer a transparent product, respectful of the body and aligned with current expectations in terms of health, ethics, and sustainability.
