Teoliance

ISO-H2

from £34.90
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Teoliance
ISO-H2

Specifically selected microbiota strains

  • Registered microbiota strains with clinically demonstrated efficacy : Lactobacillus rhamnosus GG, Lactobacillus rhamnosus GG, Lactobacillus plantarum P8, Bifidobacterium longum BL03, Bacillus coagulans IS-2®
  • Specific probiotic yeast : Saccharomyces boulardii CNCM I-1079
  • Optimal bioavailability : Individually microencapsulated microbiota strains and gastro-resistant capsules
  • Enhanced naturalness : 100% plant-based capsules
PHY605 - 30 capsules
-8%
-11%
Free delivery from £25.00 onwards
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Benefits

Functional diarrhoea refers to repeated episodes of loose or watery stools with no identifiable organic cause during medical examinations. It is one of a number of chronic intestinal disorders that reflect a dysfunction of the intestinal transit rather than an inflammatory or infectious disease. These disorders may be accompanied by bloating, intestinal gas, functional abdominal pain, accelerated intestinal transit and increased digestive sensitivity, causing digestive discomfort that can sometimes be long-lasting.

Proper bowel function depends on a complex balance between intestinal motility, the digestive mucosa and the intestinal microbiota. The microbiota is the collection of microorganisms naturally present in the digestive tract that are involved in digestion and fermentation. When this ecosystem is disrupted, it is referred to as intestinal microbiota imbalance or intestinal dysbiosis. This condition is frequently studied in the context of functional diarrhoea, bloating and diarrhoea, or irritable bowel syndrome.

In some cases, these digestive disorders are investigated in connection with bacterial overgrowth in the small intestine, known as SIBO (Small Intestinal Bacterial Overgrowth). SIBO can be associated with increased gas production, particularly hydrogen (SIBO H₂) or hydrogen sulphide (SIBO H₂S), linked to the metabolic activity of certain bacteria. These phenomena are being studied to better understand the associations between SIBO and diarrhoea, intestinal gas and disturbed intestinal microbiota.

These symptoms may also be part of irritable bowel syndrome, particularly in its forms associated with diarrhoea. Understanding them now requires a comprehensive approach that takes into account intestinal function, microbiota, diet and lifestyle.

Why choose TEOLIANCE® ISO-H2 ?

TEOLIANCE® ISO-H2 is based on a synergistic combination of rigorously selected, registered and scientifically documented microbiota strains, whose efficacy has been evaluated in clinical studies. Each capsule of TEOLIANCE® ISO-H2 delivers a precise combination of microbiota strains and a probiotic yeast, expressed in colony-forming units.

It provides 6 billion CFU of Lactobacillus rhamnosus GG, 6 billion CFU of Lactobacillus plantarum P8, 2 billion CFU of Bifidobacterium longum BL03, and 2 billion CFU of Bacillus coagulans IS-2®. The formula is completed with 5 billion CFU of Saccharomyces boulardii CNCM I-1079, a reference probiotic yeast. To preserve the integrity, viability, and stability of the strains throughout digestive transit, the formula incorporates Probio-Protect® technology, based on individual microencapsulation of each microbiota strain. The capsules are gastro-resistant, helping to limit the impact of the gastric environment and to promote the delivery of microorganisms to the intestinal tract.

The whole approach is aligned with naturalness and clean label principles, using 100% plant-based capsules, suitable for vegetarian and vegan diets.

What does science say?

The microbiota strains used in TEOLIANCE® ISO-H2 have been extensively studied scientifically, and their biological mechanism of action is well documented in the literature. Numerous studies highlight potential interesting applications.

However, to date, no health claims have been approved by European legislation for the microbiota strains Lactobacillus rhamnosus GG, Lactobacillus rhamnosus GG, Lactobacillus plantarum P8, Bifidobacterium longum BL03, Bacillus coagulans IS-2®; nor for the yeast Saccharomyces boulardii CNCM I-1079.

Despite the lack of official recognition of specific benefits, this growing interest highlights promising prospects that deserve further exploration.

The advantages of TEOLIANCE® ISO-H2

Synergistic combination of 4 microbiota strains + 1 probiotic yeast

TEOLIANCE® ISO-H2 is based on a synergistic combination of five microorganisms selected for their biological complementarity and scientific relevance in the study of the intestinal microbiota. The formula combines three lactic bacteria belonging to genera widely studied in the scientific literature: Lactobacillus rhamnosus GG and Lactobacillus plantarum P8, as well as Bifidobacterium longum BL03.

These strains are naturally present in the human microbiota and are the subject of numerous publications. The formulation is completed by Bacillus coagulans IS-2®, a spore-forming bacterium, whose natural ability to form spores gives it particular robustness against the constraints of the digestive environment. Finally, the probiotic yeast Saccharomyces boulardii CNCM I-1079 completes this combination. This precisely identified and registered yeast is widely documented in microbiology for its structural properties and stability.

All strains included in TEOLIANCE® ISO-H2 are clearly identified, genetically characterized, and documented, with controlled dosages per capsule. Their selection follows a rigorous formulation approach, based on traceability, raw material quality, and scientific consistency, in compliance with the European regulatory framework applicable to microorganism-based dietary supplements.

Spore-forming strain Bacillus coagulans IS-2® scientifically selected and resistant

The strain Bacillus coagulans IS-2® included in TEOLIANCE® ISO-H2 is a precisely identified and registered spore-forming bacterium belonging to the Bacillus genus. Its natural ability to form spores provides high robustness against the constraints of the digestive environment.

This biological characteristic explains the interest in this strain for formulations intended for the intestinal environment. The spores allow Bacillus coagulans IS-2® to pass through the different stages of the digestive tract while maintaining viability, before germination in the intestine. This strain has been the subject of numerous scientific works and clinical studies conducted in humans, contributing to comprehensive documentation of its characteristics and use. As a registered strain, Bacillus coagulans IS-2® benefits from full traceability, strict quality control, and lot-to-lot consistency.

Its integration into TEOLIANCE® ISO-H2 follows a rigorous formulation approach, based on the selection of stable microorganisms, documented and complementary, in compliance with the European regulatory framework.

Probiotic yeast Saccharomyces boulardii CNCM I-1079, optimal resistance

The yeast Saccharomyces boulardii CNCM I-1079 is a precisely identified and documented strain, referenced in the National Collection of Microorganism Cultures (CNCM), ensuring its traceability, reproducibility, and stability. It is a specific variant of Saccharomyces cerevisiae, first identified in the early 20th century by microbiologist Henri Boulard from yeasts naturally present on the skin of tropical fruits, traditionally used in some fermented preparations. Unlike bacterial probiotics, Saccharomyces boulardii is a yeast, whose fungal structure gives it particular robustness against digestive constraints, notably pH variations and bile salts. These biological characteristics explain the scientific interest in this yeast within microorganism-based formulations, and its inclusion in the TEOLIANCE® ISO-H2 formula, based on the choice of clearly identified, characterized, and historically studied strains.

Gastro-resistant capsules, strain bioavailability and Probio-Protect® technology

Bioavailability corresponds to the proportion of an active ingredient actually available in the body after ingestion. For a microorganism-based dietary supplement, it depends in particular on the ability of live microorganisms to withstand the physical and chemical constraints of the digestive tract, such as gastric acidity, before reaching the intestinal environment.

The formulation of TEOLIANCE® ISO-H2 relies on gastro-resistant capsules, designed to preserve the integrity of microbiota strains and yeast throughout digestive transit and allow their release in the intestine. This galenic choice aligns with a respectful approach to intestinal physiology and the natural functioning of the intestinal microbiota.

THERASCIENCE Laboratory has developed the patented Probio-Protect® technology, used in the formulation of TEOLIANCE® ISO-H2. This process is based on individual microencapsulation of strains, each microorganism being protected by a plant-based coating specifically designed to accompany its release in the intestinal environment. This microencapsulation aims to preserve the quality of strains during encapsulation, protect them from environmental factors such as oxidation, light, heat, or humidity, and prevent premature interactions between formula components.

Certain strains present in TEOLIANCE® ISO-H2, such as Bacillus coagulans IS-2® and the yeast Saccharomyces boulardii, have specific biological characteristics. Bacillus coagulans IS-2® is a spore-forming bacterium capable of forming spores, a natural structure that provides resistance to digestive conditions. Saccharomyces boulardii, on the other hand, is a yeast recognized for its robustness against pH variations. Thanks to this combination of gastro-resistant capsules and Probio-Protect® microencapsulation, TEOLIANCE® ISO-H2 follows a demanding formulation approach, combining controlled bioavailability, strain stability, and technological consistency, for a dietary supplement dedicated to intestinal balance.

Naturalness and clean label supporting intestinal balance

For THERASCIENCE Laboratory, naturalness is part of a global formulation approach and is not limited to the origin of ingredients. It relies on a rigorous selection of components, respect for intestinal physiology, and consistency with current scientific knowledge on the intestinal microbiota and digestive function.

The formula notably includes the yeast Saccharomyces boulardii CNCM I-1079, a microorganism naturally present in the environment. This yeast was initially isolated from the skin of tropical fruits, illustrating its natural origin and connection to the plant world. Its use follows a logic of understanding and respecting microbial balances. TEOLIANCE® ISO-H2 was designed according to strict criteria of quality, purity, and scientific relevance, to offer a microorganism-based dietary supplement aligned with the natural functioning of the intestine. The formulation favors a streamlined composition, with intentionally limited excipients, selected for their common use and digestive compatibility, in a Clean Label approach. The use of 100% vegetable capsules reinforces this naturalness approach.

The formula is guaranteed free from lactose and gluten-based ingredients, to meet the expectations of people following specific diets or with digestive sensitivity, while maintaining a high level of quality, traceability, and control over the formulation.

Using advice

1 to 2 capsules, twice a day, 30 minutes before a meal.

Directions for use:

  • After receipt, store the product in a cool dry place.

Food supplements should be used as part of a healthy lifestyle and must not be used as a substitute for a varied and balanced diet. Do not exceed recommended daily dose. Keep this product out of the reach of young children. 

If using several dietary supplements, ask your healthcare professional for guidance.

Ingredients

Saccharomyces boulardii, plant origin coating: hydroxypropylmethylcellulose, bulking agent: acacia gum**, Bifidobacterium longum BL03, Bacillus coagulans IS-2®Lactobacillus plantarum P8, Lactobacillus rhamnosus GG, anti-caking agent: fatty acids.

**produced from organic farming

Net weight : 18.17 g

Nutritional analysis

  For 1 capsule
Lactobacillus rhamnosus GG 6 billion CFU*
Lactobacillus plantarum P8 6 billion CFU*
Bifidobacterium longum BL03 6 billion CFU*
Bacillus coagulans IS-2 ® 2 billion CFU*
Saccharomyces boulardii5 5 billion CFU*


*CFU: Colony Forming Units

Quality labels

Probio-Protect
Patented biotechnology for the individual microencapsulation of microbiota strains, allowing the release of active ingredients in the intestine and thus guaranteeing optimal efficacy and synergy of action
Our health records
IMMUNE SYSTEM - Laboratoire THERASCIENCE
IMMUNE SYSTEM
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