Creatine is a molecule naturally synthesised by the body from three amino acids (L-arginine, glycine and L-methionine). It is then transported to tissues with high energy demand, particularly muscles, where it is stored in the form of phosphocreatine. This system plays a key role in the rapid production of energy, by enabling the regeneration of ATP (adenosine triphosphate), the main source of cellular energy, particularly used during short, repeated and high-intensity efforts. In this context, an adequate intake of creatine helps to support physical performance during successive sets of very intense, short-duration exercises, particularly from a daily intake of 3 g.
Creatine requirements may be increased in individuals engaging in intense or repeated physical activities, due to greater demand on muscle energy reserves. Furthermore, dietary intake mainly relies on the consumption of meat and fish. As an indication, approximately 500 g of red meat provides around 2.5 g of creatine, which remains below the daily intake associated with the physiological effects described. Moreover, certain cooking methods, particularly at high temperatures, may alter the creatine content of foods. Vegetarian or vegan diets, naturally low in creatine, may also lead to lower intakes.
An optimal intake of creatine helps to improve physical performance during successive sets of very intense, short-duration exercises, particularly in high-intensity sports activities.
Creatine is particularly useful for athletes who wish to improve their ability to perform these successive efforts. Used as part of an appropriate training programme, creatine is therefore part of an approach aimed at supporting performance goals and athletic progression. This effect also extends, with advancing age and in combination with resistance training, to the ability to enhance the effect of resistance training on muscle strength in adults over 55, in compliance with the defined conditions of use.
Beyond muscle, creatine is attracting growing interest for its role in brain energy metabolism, in relation to mental fatigue and cognitive functions. Furthermore, certain amino acids such as L-glutamine and taurine are being studied for their involvement in digestive balance, immune support and metabolic adaptations. Carbohydrate substrates, for their part, contribute to the overall and rapid energy supply, ideal during exercise. Together, these bio-active ingredients are part of an approach aimed at supporting physical performance and sports recovery.
Why choose PHYSIOMANCE Creatine+?
PHYSIOMANCE® Creatine+ stands out for its comprehensive formulation combining 4 synergistic bio-active ingredients, selected for their complementarity in the context of physical performance, recovery and overall body support. Each serving provides a precisely dosed combination of: 3 g of creatine monohydrate Creapure®, 750 mg of taurine, 1.5 g of L-glutamine and 2 g of carbohydrates.
The 3 g dose selected for creatine corresponds to the daily intake for which it is recognised to improve physical performance - during successive sets of very intense, short-duration exercises. Our Creapure® creatine is provided in monohydrate form, ultra-pure and produced according to strict quality standards, thereby ensuring high purity, rigorous traceability and absence of contaminants. This manufacturing quality helps to ensure safe and well-tolerated use, including in athletes.
PHYSIOMANCE® Creatine+ includes taurine and L-glutamine, two amino acids of growing interest, as well as dextrose, in order to complete this synergy and best support effort.
Finally, as part of an enhanced natural approach, PHYSIOMANCE® Creatine+ is based on a carefully designed formulation, with a natural peach flavour, a sweetener of natural origin derived from fermentation, and no colouring, in line with our Clean label® THERASCIENCE requirements.
What does the science say?
The benefits of creatine have been subject to scientific evaluation by the European Food Safety Authority (EFSA), making it possible to establish specific physiological effects under defined intake conditions.
With a daily intake of 3 g, creatine contributes:
- - To improving physical performance during successive sets of very intense, short-duration exercises;
- - To enhancing the effect of resistance training on muscle strength in adults over 55, as part of resistance training.
These effects are part of an appropriate use, particularly in combination with regular physical activity.
To date, European legislation has not approved any health claims for taurine, glutamine and dextrose.
Although no specific benefit is officially recognised, these bio-active ingredients are attracting growing interest and open up promising perspectives that deserve to be explored.
They are notably the subject of numerous scientific studies that have highlighted their biological mechanisms of action and interesting potential applications.
The benefits of PHYSIOMANCE® Creatine+

Synergistic combination of 4 bio-active ingredients
PHYSIOMANCE® Creatine+ is based on a structured combination of 4 complementary bio-active ingredients: Creapure® creatine monohydrate, taurine, L-glutamine and dextrose. This formulation is part of a global approach aimed at supporting the body’s needs in situations of physical demand, recovery and metabolic adaptation.
At the heart of this synergy, creatine is involved in the mechanisms of rapid energy production, while the amino acids complement this action by integrating into processes related to muscle recovery and the overall functioning of the body. Dextrose contributes to the nutritional environment of the formulation, in line with strategies combining creatine and carbohydrate intake. This combination of bio-active ingredients thus makes it possible to offer an integrated approach, in line with needs related to performance, recovery and overall physiological support.
Creapure® creatine: purity, quality and scientific reference
PHYSIOMANCE® Creatine+ provides creatine exclusively in the form of Creapure® creatine monohydrate. This form is currently the most documented in scientific literature and constitutes a reference in studies on creatine, particularly in the context of physical performance. With a daily intake of 3 g, creatine helps to improve physical performance during successive sets of very intense, short-duration exercises.
The monohydrate form is characterised by a simple and stable structure, allowing efficient use by muscle tissues, particularly in situations of high energy demand. It is directly involved in the mechanisms of rapid energy production, in connection with the regeneration of ATP (adenosine triphosphate, the main source of cellular energy) within muscle cells engaged during intense efforts.
The Creapure® creatine monohydrate is recognised as one of the purest forms available, linked to the rigour of its manufacturing process. Produced in Germany according to high industrial standards and compliant with GMP standards (the strictest quality standards), it undergoes quality controls at each stage of the manufacturing process, ensuring the absence of contaminants, impurities or undesirable substances.
This control of manufacturing processes also ensures consistent stability and reproducibility, helping to provide creatine suitable for use within a rigorous nutritional framework, in line with the expectations of athletes and healthcare professionals. This selection requirement makes it possible to offer creatine combining quality, safety of use and scientific reference, in line with a structured nutritional approach.
Cofactors: a complementary and integrated approach
The PHYSIOMANCE® Creatine+ formula is enriched with taurine and L-glutamine, two amino acids involved in numerous physiological processes. Their presence is part of an approach aimed at supporting the body’s needs beyond energy metabolism alone.
Taurine is studied for its role in cellular balance. In addition, L-glutamine, for its part, is particularly involved in rapidly renewing tissues. Together, these amino acids act ideally during physiological adaptations related to exercise and sports recovery.
Dextrose, included in moderate amounts, completes this formulation by contributing to rapid energy supply and fitting within nutritional approaches combining creatine and carbohydrates. Its dosage has been designed to fit into a balanced formula, compatible with daily use.
All these cofactors thus help to reinforce the consistency of the formula, as part of a logic of nutritional synergy adapted to the needs of the body subjected to increased physical and physiological demands.
Enhanced naturalness
Products from THERASCIENCE Laboratory are developed with particular attention to the quality of bio-active ingredients and the consistency of formulations, in compliance with the requirements of Physionutrition®.
PHYSIOMANCE® Creatine+ offers a formula characterised by a clear composition, while being adapted to different dietary profiles. Our formulation is guaranteed free from gluten- and lactose-based ingredients, and is suitable for vegetarian and vegan diets. It is developed with a natural flavour (peach taste) and a sweetener of natural origin (steviol glycosides derived from fermentation), with no added colouring. This selection of ingredients makes it possible to offer a controlled formula, in line with current expectations regarding naturalness.
PHYSIOMANCE® Creatine+ is part of the Clean Label® THERASCIENCE approach, guaranteeing a transparent formulation and a high level of quality requirements, making it possible to offer a streamlined and targeted formula.