Choline is an essential nutrient for physiological balance, involved in numerous metabolic pathways and in the regulation of key biological functions. The body synthesizes small amounts, generally insufficient to meet daily requirements, highlighting the importance of an adequate and regular intake through diet or supplementation.
Choline is mainly found in eggs, liver, soy, meat, fish, and certain cruciferous vegetables. Although it is also present in plant sources such as soy or cauliflower, it is predominantly supplied by animal products. In this context, choline supplementation may be considered for individuals following a vegetarian or vegan diet. Furthermore, dietary intakes can vary and may sometimes be reduced by preparation methods, which can limit actual intake.
Among its major roles, choline contributes to the normal metabolism of homocysteine, naturally present in the body. This function is part of metabolic pathways involving methylation reactions, which contribute to overall biochemical balance and proper cellular function.
Additionally, choline contributes to the maintenance of normal liver function as well as normal lipid metabolism. It is involved in the synthesis of phosphatidylcholine, a phospholipid essential to the structure of cell membranes and to the physiological mechanisms of lipid handling by the liver. Phosphatidylcholine is notably involved in the assembly and secretion of very-low-density lipoproteins (VLDL), responsible for transporting endogenous lipids, primarily triglycerides, from the liver to peripheral tissues, as well as in physiological processes associated with bile production and secretion, linked to lipid metabolism.
Choline bitartrate is a form of choline used in nutrition, thus contributing to the maintenance of normal metabolic functions related to the liver, lipid metabolism, and homocysteine.
Why choose PHYSIOMANCE® Bitartrate de choline ?
PHYSIOMANCE® Bitartrate de choline provides 668.5 mg of choline bitartrate per capsule, including 275 mg of active choline. Choline bitartrate is a stable, highly bioavailable, and natural form, derived from wine production.
Formulated without artificial colorings or additives, this dietary supplement meets the rigorous Therascience Clean Label standards.
Its composition is guaranteed free from lactose- or gluten-based ingredients, free from nanoparticles and colorants, and is suitable for vegans. Its 100% vegetable capsules ensure enhanced naturalness. PHYSIOMANCE® Bitartrate de choline is a single-ingredient product, allowing personalized management, with optimal traceability and enhanced safety.
What does science say?
The health benefits of choline bitartrate are widely validated by the European Food Safety Authority (EFSA), which recognizes that it contributes to:
- - Normal homocysteine metabolism
- - The maintenance of normal liver function
- - Normal lipid metabolism
The key benefits of PHYSIOMANCE® Bitartrate de Choline

Choline in the form of Choline Bitartrate
The THERASCIENCE Laboratory has selected choline in the form of choline bitartrate, a stable and highly bioavailable form. Water-soluble, it ensures an efficient supply of active choline.
This molecule is mainly found in eggs, liver, meat, fish, as well as certain legumes and nuts. However, dietary intakes are often insufficient: NHANES data (2020) showed that the majority of the population, including pregnant women, do not meet their daily choline requirements. To address these needs, the THERASCIENCE Laboratory has selected choline in the form of choline bitartrate, a high-quality reference form.
This form uses exclusively natural L(+) tartaric acid, derived from winemaking, ensuring purity, optimal stability, and high bioavailability, for an efficient supply of active choline.
Optimal Dosage
Each capsule provides 668.5 mg of choline bitartrate, equivalent to 550 mg of active choline. This corresponds to an intake equivalent to about 2 eggs (one egg provides on average 120 to 140 mg of choline), a level difficult to achieve daily through diet alone.
This dosage thus allows for an efficient and bioavailable intake, while ensuring good digestive tolerance.
This dosage respects the recommended nutritional intakes while ensuring optimal physiological efficiency.
This quantity has been carefully selected to meet physiological needs without excess, thus ensuring safe, well-tolerated supplementation suitable for daily use.
Enhanced Naturalness
PHYSIOMANCE® Bitartrate de choline embodies the commitment of the THERASCIENCE Laboratory to enhanced naturalness and a formulation respectful of the body.
This dietary supplement is formulated from naturally sourced choline, without coloring agents or excipients, and encapsulated in 100% vegetable capsules. It contains no gluten- or lactose-based ingredients, and is fully suitable for vegetarian and vegan diets. This requirement for purity and transparency reflects the aim to offer a high-quality, bioavailable, and safe product, aligned with current expectations in health, ethics, and sustainability.
This purity requirement expresses a commitment to offer a transparent product, respectful of the body, and aligned with current expectations in health, ethics, and sustainability.
Single-ingredient: targeted, effective, and personalized supplementation
Discover the single-ingredients by Therascience, developed by our Laboratory expert in Physionutrition!
To ensure effective supplementation, tailored to each of your needs, the THERASCIENCE Laboratory develops a wide range of single-ingredient formulas, always guaranteeing product quality and the effectiveness of its active ingredients! The single-ingredients by Therascience allow:
- Personalization of each supplementation to adapt to your needs,
- Precise and micro-targeted responses,
- Supplementation without risk of potential overdose of certain vitamins, minerals, or trace elements.